Tandem phosphorylation within an intrinsically disordered region regulates ACTN4 function

Tandem phosphorylation within an intrinsically disordered region regulates ACTN4 function

Phosphorylated residues occur preferentially in the intrinsically disordered regions of eukaryotic proteins. In the disordered amino-terminal region of human a-actinin-4 (ACTN4), Tyr[superscript 4] and Tyr[superscript 31] are phosphorylated in cells stimulated with epidermal growth factor (EGF), and...

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Bibliographic Details
Main Authors: Travers, Timothy, Shao, Hanshuang, Wells, Alan, Camacho, Carlos J., Joughin, Brian Alan, Lauffenburger, Douglas A
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2015
Online Access:http://hdl.handle.net/1721.1/99497

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http://hdl.handle.net/1721.1/99497

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