A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects

We describe a rapid method to accurately measure the cytotoxicity of mammalian cells upon exposure to various drugs. Using this assay, we obtain survival data in a fraction of the time required to perform the traditional clonogenic survival assay, considered the gold standard. The dynamic range of t...

Full description

Bibliographic Details
Main Authors: Valiathan, Chandni, McFaline, Jose Luis, Samson, Leona D.
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99508
https://orcid.org/0000-0002-7112-1454