A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects
We describe a rapid method to accurately measure the cytotoxicity of mammalian cells upon exposure to various drugs. Using this assay, we obtain survival data in a fraction of the time required to perform the traditional clonogenic survival assay, considered the gold standard. The dynamic range of t...
Main Authors: | Valiathan, Chandni, McFaline, Jose Luis, Samson, Leona D. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Center for Environmental Health Sciences |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
|
Online Access: | http://hdl.handle.net/1721.1/99508 https://orcid.org/0000-0002-7112-1454 |
Similar Items
-
Rapid colorimetric assay for cellular growth and survival : application to proliferation and cytotoxicity assays /
by: 410956 Mosmann, Tim -
Mechanism of acquired temozolomide resistance in glioblastoma
by: McFaline-Figueroa, José L
Published: (2014) -
Identifying a transcriptional signature for cell sensitivity to the cancer chemotherapy agent, BCNU
by: Valiathan, Chandni Rajan
Published: (2011) -
Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation
by: Ngo, Le P, et al.
Published: (2020) -
A Rapid and Reliable Absorbance Assay to Identify Drug–Drug Interactions with Thiopurine Drugs
by: Drake A. Russell, et al.
Published: (2024-12-01)