Inter-individual variation in DNA repair capacity: A need for multi-pathway functional assays to promote translational DNA repair research

Why does a constant barrage of DNA damage lead to disease in some individuals, while others remain healthy? This article surveys current work addressing the implications of inter-individual variation in DNA repair capacity for human health, and discusses the status of DNA repair assays as potential...

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Bibliographic Details
Main Authors: Nagel, Zachary D., Chaim, Isaac Alexander, Samson, Leona D
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99515
https://orcid.org/0000-0003-1787-046X
https://orcid.org/0000-0002-7112-1454