Repair of endogenous DNA base lesions modulate lifespan in mice

Repair of endogenous DNA base lesions modulate lifespan in mice

The accumulation of DNA damage is thought to contribute to the physiological decay associated with the aging process. Here, we report the results of a large-scale study examining longevity in various mouse models defective in the repair of DNA alkylation damage, or defective in the DNA damage respon...

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Bibliographic Details
Main Authors: Meira, Lisiane B., Calvo, Jennifer A., Shah, Dharini, Klapacz, Joanna, Moroski-Erkul, Catherine A., Bronson, Roderick T., Samson, Leona D
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99516
https://orcid.org/0000-0002-7112-1454

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http://hdl.handle.net/1721.1/99516
https://orcid.org/0000-0002-7112-1454

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