Human (α2→6) and Avian (α2→3) Sialylated Receptors of Influenza A Virus Show Distinct Conformations and Dynamics in Solution

Human (α2→6) and Avian (α2→3) Sialylated Receptors of Influenza A Virus Show Distinct Conformations and Dynamics in Solution

Differential interactions between influenza A virus protein hemagglutinin (HA) and α2→3 (avian) or α2→6 (human) sialylated glycan receptors play an important role in governing host specificity and adaptation of the virus. Previous analysis of HA–glycan interactions with trisaccharides showed that, i...

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Bibliographic Details
Main Authors: Sassaki, Guilherme L., Elli, Stefano, Rudd, Timothy R., Macchi, Eleonora, Yates, Edwin A., Naggi, Annamaria, Raman, Rahul, Torri, Giangiacomo, Guerrini, Marco, Shriver, Zachary H., Sasisekharan, Ram
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/99521
https://orcid.org/0000-0001-9344-0205
https://orcid.org/0000-0002-2085-7840

Internet

http://hdl.handle.net/1721.1/99521
https://orcid.org/0000-0001-9344-0205
https://orcid.org/0000-0002-2085-7840

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