Genomic mining of prokaryotic repressors for orthogonal logic gates

Genetic circuits perform computational operations based on interactions between freely diffusing molecules within a cell. When transcription factors are combined to build a circuit, unintended interactions can disrupt its function. Here, we apply 'part mining' to build a library of 73 TetR...

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Bibliographic Details
Main Authors: Tamsir, Alvin, Clancy, Kevin, Peterson, Todd, Stanton, Brynne C., Nielsen, Alec Andrew, Voigt, Christopher A.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/99526
https://orcid.org/0000-0003-0844-4776
https://orcid.org/0000-0003-2171-8460