Isocost Lines Describe the Cellular Economy of Genetic Circuits

Genetic circuits in living cells share transcriptional and translational resources that are available in limited amounts. This leads to unexpected couplings among seemingly unconnected modules, which result in poorly predictable circuit behavior. In this study, we determine these interdependencies b...

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Bibliographic Details
Main Authors: Yazbek, John, Huang, Hsin-Ho, Chung, Hattie, Weiss, Ron, Del Vecchio, Domitilla, Gyoergy, Andras, Jimenez Zarco, Jose I., Del Vecchio, Domitilla
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99533
https://orcid.org/0000-0003-0396-2443
https://orcid.org/0000-0003-2435-480X
https://orcid.org/0000-0001-6472-8576
https://orcid.org/0000-0002-4784-3772