Phenotypic states become increasingly sensitive to perturbations near a bifurcation in a synthetic gene network

Microorganisms often exhibit a history-dependent phenotypic response after exposure to a stimulus which can be imperative for proper function. However, cells frequently experience unexpected environmental perturbations that might induce phenotypic switching. How cells maintain phenotypic states in t...

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Bibliographic Details
Main Authors: Axelrod, Kevin, Sanchez, Alvaro, Gore, Jeff
Other Authors: Massachusetts Institute of Technology. Department of Physics
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2015
Online Access:http://hdl.handle.net/1721.1/99641
https://orcid.org/0000-0003-4583-8555