Assaying the kinetics of protein denaturation catalyzed by AAA+ unfolding machines and proteases
ATP-dependent molecular machines of the AAA+ superfamily unfold or remodel proteins in all cells. For example, AAA+ ClpX and ClpA hexamers collaborate with the self-compartmentalized ClpP peptidase to unfold and degrade specific proteins in bacteria and some eukaryotic organelles. Although degradati...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
National Academy of Sciences (U.S.)
2015
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| Online Access: | http://hdl.handle.net/1721.1/99647 https://orcid.org/0000-0002-7390-3580 https://orcid.org/0000-0002-1719-5399 |