Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome
Proteasomes are central regulators of protein homeostasis in eukaryotes. Proteasome function is vulnerable to environmental insults, cellular protein imbalance and targeted pharmaceuticals. Yet, mechanisms that cells deploy to counteract inhibition of this central regulator are little understood. To...
| Main Authors: | , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
eLife Sciences Publications, Ltd.
2015
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| Online Access: | http://hdl.handle.net/1721.1/99666 https://orcid.org/0000-0003-1307-882X |