Copper-Catalyzed Regioselective Ortho C-H Cyanation of Vinylarenes

A copper-based catalytic technique for the regioselective ortho C-H cyanation of vinylarenes has been developed. This method provides an effective means for the selective functionalization of vinylarene derivatives. A copper-catalyzed cyanative dearomatization mechanism is proposed to account for th...

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Bibliographic Details
Main Authors: Yang, Yang, Buchwald, Stephen Leffler
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Wiley Blackwell 2015
Online Access:http://hdl.handle.net/1721.1/99668
https://orcid.org/0000-0003-3875-4775