Identification of drugs as single agents or in combination to prevent carcinoma dissemination in a microfluidic 3D environment

Experiments were performed in a modified microfluidic platform recapitulating part of the in vivo tumor microenvironment by co-culturing carcinoma cell aggregates embedded in a three-dimensional (3D) collagen scaffold with human umbilical vein endothelial cells (HUVECs). HUVECs were seeded in one ch...

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Bibliographic Details
Main Authors: Bai, Jing, Tu, Ting-Yuan, Kim, Choong, Thiery, Jean Paul, Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Impact Journals/National Center for Biotechnology Information (U.S.) 2015
Online Access:http://hdl.handle.net/1721.1/99699
https://orcid.org/0000-0002-7232-304X