Cell Invasion Dynamics into a Three Dimensional Extracellular Matrix Fibre Network

The dynamics of filopodia interacting with the surrounding extracellular matrix (ECM) play a key role in various cell-ECM interactions, but their mechanisms of interaction with the ECM in 3D environment remain poorly understood. Based on first principles, here we construct an individual-based, force...

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Bibliographic Details
Main Authors: Kim, Min-Cheol, Silberberg, Yaron R., Whisler, Jordan Ari, Kamm, Roger Dale, Asada, Harry
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2015
Online Access:http://hdl.handle.net/1721.1/99731
https://orcid.org/0000-0002-3299-9424
https://orcid.org/0000-0001-6649-9463
https://orcid.org/0000-0003-3155-6223
https://orcid.org/0000-0002-7232-304X