Host Cell Phosphatidylcholine Is a Key Mediator of Malaria Parasite Survival during Liver Stage Infection

During invasion, Plasmodium, the causative agent of malaria, wraps itself in a parasitophorous vacuole membrane (PVM), which constitutes a critical interface between the parasite and its host cell. Within hepatocytes, each Plasmodium sporozoite generates thousands of new parasites, creating high dem...

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Bibliographic Details
Main Authors: Itoe, Maurice A., Cabal, Ghislain G., Real, Eliana, Zuzarte-Luis, Vanessa, Bhatia, Sangeeta N., Frischknecht, Friedrich, Thiele, Christoph, Shevchenko, Andrej, Mota, Maria M., Sampaio, Julio L., March-Riera, Sandra, Bhatia, Sangeeta N
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99873
https://orcid.org/0000-0002-1293-2097