Disease Detection by Ultrasensitive Quantification of Microdosed Synthetic Urinary Biomarkers

The delivery of exogenous agents can enable noninvasive disease monitoring, but existing low-dose approaches require complex infrastructure. In this paper, we describe a microdose-scale injectable formulation of nanoparticles that interrogate the activity of thrombin, a key regulator of clotting, an...

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Bibliographic Details
Main Authors: Gaylord, Shonda T., Ngan, Kevin C., Dumont Milutinovic, Milena, Kwong, Gabriel A., Bhatia, Sangeeta N., Walt, David R., Warren, Andrew David
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/99875
https://orcid.org/0000-0002-1293-2097
https://orcid.org/0000-0003-1948-0289