Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay

Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay

The NF-κB transcription factor family plays a central role in innate immunity and inflammation processes and is frequently dysregulated in cancer. We developed an NF-κB functional assay in yeast to investigate the following issues: transactivation specificity of NF-κB proteins acting as homodimers o...

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Bibliographic Details
Main Authors: Sharma, Vasundhara, Jordan, Jennifer J., Ciribilli, Yari, Resnick, Michael A., Bisio, Alessandra, Inga, Alberto
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2015
Online Access:http://hdl.handle.net/1721.1/99881

Internet

http://hdl.handle.net/1721.1/99881

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