Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay
The NF-κB transcription factor family plays a central role in innate immunity and inflammation processes and is frequently dysregulated in cancer. We developed an NF-κB functional assay in yeast to investigate the following issues: transactivation specificity of NF-κB proteins acting as homodimers o...
Main Authors: | Sharma, Vasundhara, Jordan, Jennifer J., Ciribilli, Yari, Resnick, Michael A., Bisio, Alessandra, Inga, Alberto |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2015
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Online Access: | http://hdl.handle.net/1721.1/99881 |
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