Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay
The NF-κB transcription factor family plays a central role in innate immunity and inflammation processes and is frequently dysregulated in cancer. We developed an NF-κB functional assay in yeast to investigate the following issues: transactivation specificity of NF-κB proteins acting as homodimers o...
Main Authors: | Sharma, Vasundhara, Jordan, Jennifer J., Ciribilli, Yari, Resnick, Michael A., Bisio, Alessandra, Inga, Alberto |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2015
|
Online Access: | http://hdl.handle.net/1721.1/99881 |
Similar Items
-
ETV7 reduces inflammatory responses in breast cancer cells by repressing the TNFR1/NF-κB axis
by: Erna Marija Meškytė, et al.
Published: (2023-04-01) -
NFκB (RelA) mediates transactivation of hnRNPD in oral cancer cells
by: Vikas Kumar, et al.
Published: (2022-04-01) -
DNA-dependent protein kinase catalytic subunit binds to the transactivation domain 1 of NF-κB p65
by: Yuta Hasegawa, et al.
Published: (2023-09-01) -
EYA4 inhibits hepatocellular carcinoma growth and invasion by suppressing NF-κB-dependent RAP1 transactivation
by: Shi-Jing Mo, et al.
Published: (2018-04-01) -
Nickel(II) Complex of Polyhydroxybenzaldehyde N4-Thiosemicarbazone Exhibits Anti-Inflammatory Activity by Inhibiting NF-κB Transactivation
by: Shawish, H.B., et al.
Published: (2014)