ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets

ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets

X chromosome inactivation (XCI) depends on the long noncoding RNA Xist and its recruitment of Polycomb Repressive Complex 2 (PRC2). PRC2 is also targeted to other sites throughout the genome to effect transcriptional repression. Using XCI as a model, we apply an unbiased proteomics approach to isola...

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Bibliographic Details
Main Authors: Sarma, Kavitha, Cifuentes-Rojas, Catherine, Ergun, Ayla, Jeon, Yesu, Sadreyev, Ruslan, Lee, Jeannie T., White, Forest M., Del Rosario, Amanda M
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99944
https://orcid.org/0000-0002-1545-1651

Internet

http://hdl.handle.net/1721.1/99944
https://orcid.org/0000-0002-1545-1651

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