A P-loop mutation in Gα subunits prevents transition to the active state : implications for G-protein signaling in fungal pathogenesis

Heterotrimeric G-proteins are molecular switches integral to a panoply of different physiological responses that many organisms make to environmental cues. The switch from inactive to active Gαβγ heterotrimer relies on nucleotide cycling by the Gα subunit: exchange of GTP for GDP activates Gα, where...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Siderovski, David P., Bosch, Dustin E., Willard, Francis S., Kimple, Adam J., Willard, Melinda D., Naqvi, Naweed Issak., Ramanujam, Ravikrishna.
Övriga upphovsmän:	School of Biological Sciences
Materialtyp:	Journal Article
Språk:	English
Publicerad:	2013
Ämnen:	DRNTU::Science::Biological sciences
Länkar:	https://hdl.handle.net/10356/100154 http://hdl.handle.net/10220/10955

Internet

https://hdl.handle.net/10356/100154
http://hdl.handle.net/10220/10955

A P-loop mutation in Gα subunits prevents transition to the active state : implications for G-protein signaling in fungal pathogenesis

Internet

Liknande verk