An improved classification of G-protein-coupled receptors using sequence-derived features

Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structures of GPCRs are largely unavailable; however, a large number of GPCR primary sequences are known. To facilitate the ide...

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Detalles Bibliográficos
Autores principales: Peng, Zhen-Ling, Yang, Jian-Yi, Chen, Xin
Otros Autores: School of Physical and Mathematical Sciences
Formato: Journal Article
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://hdl.handle.net/10356/100530
http://hdl.handle.net/10220/17875