Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast

Background: The regulatory mechanism of recombination is one of the most fundamental problems in genomics, with wide applications in genome wide association studies (GWAS), birth-defect diseases, molecular evolution, cancer research, etc. Recombination events cluster into short genomic regions calle...

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Bibliographic Details
Main Authors: Wu, Min, Kwoh, Chee-Keong, Li, Xiaoli, Zheng, Jie
Other Authors: School of Computer Engineering
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/100580
http://hdl.handle.net/10220/24144