Promoter sequence determines the relationship between expression level and noise

The ability of cells to accurately control gene expression levels in response to extracellular cues is limited by the inherently stochastic nature of transcriptional regulation. A change in transcription factor (TF) activity results in changes in the expression of its targets, but the way in which c...

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Bibliographic Details
Main Authors: Carey, Lucas B., van Dijk, David., Sloot, Peter M. A., Kaandorp, Jaap A., Segal, Eran.
Other Authors: School of Computer Engineering
Format: Journal Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/100847
http://hdl.handle.net/10220/9866