Meta-analysis of genomic and proteomic features to predict synthetic lethality of yeast and human cancer
A major goal in cancer medicine is to find selective drugs with reduced side-effect. A pair of genes is called synthetic lethality (SL) if mutations of both genes will kill a cell while mutation of either gene alone will not. Hence, a gene in SL interactions with a cancer-specific mutated gene will...
Main Authors: | , , , , , |
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Other Authors: | |
Format: | Conference Paper |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/100938 http://hdl.handle.net/10220/18183 |