Toxoplasma gondii is dependent on glutamine and alters migratory profile of infected host bone marrow derived immune cells through SNAT2 and CXCR4 pathways

The obligate intracellular parasite, Toxoplasma gondii, disseminates through its host inside infected immune cells. We hypothesize that parasite nutrient requirements lead to manipulation of migratory properties of the immune cell. We demonstrate that 1) T. gondii relies on glutamine for optimal inf...

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Bibliographic Details
Main Authors: De Miguel, Zurine, Manley, Nathan C., Lee, I-Ping, Evans, Andrew K., Yang, Cissy, Works, Melissa G., Kumar, Vineet, Sapolsky, Robert M.
Other Authors: Bogyo, Matthew
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/101134
http://hdl.handle.net/10220/24140