Toxoplasma gondii is dependent on glutamine and alters migratory profile of infected host bone marrow derived immune cells through SNAT2 and CXCR4 pathways
The obligate intracellular parasite, Toxoplasma gondii, disseminates through its host inside infected immune cells. We hypothesize that parasite nutrient requirements lead to manipulation of migratory properties of the immune cell. We demonstrate that 1) T. gondii relies on glutamine for optimal inf...
Main Authors: | De Miguel, Zurine, Manley, Nathan C., Lee, I-Ping, Evans, Andrew K., Yang, Cissy, Works, Melissa G., Kumar, Vineet, Sapolsky, Robert M. |
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Other Authors: | Bogyo, Matthew |
Format: | Journal Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/101134 http://hdl.handle.net/10220/24140 |
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