Solid-Phase synthesis and biological evaluation of N-dipeptido L-homoserine lactones as quorum sensing activators

Bacteria use small signaling molecules to communicate in a process termed “quorum sensing” (QS), which enables the coordination of survival strategies, such as production of virulence factors and biofilm formation. In Gram-negative bacteria, these signaling molecules are a series of N-acylated L-hom...

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Bibliographic Details
Main Authors: Hansen, Mette R., Le Quement, Sebastian T., Jakobsen, Tim H., Skovstrup, Søren, Taboureau, Olivier, Tolker-Nielsen, Tim, Givskov, Michael, Nielsen, Thomas E.
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/101266
http://hdl.handle.net/10220/19692