Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

Several Sox-Oct transcription factor (TF) combinations have been shown to cooperate on diverse enhancers to determine cell fates. Here, we developed a method to quantify biochemically the Sox-Oct cooperation and assessed the pairing of the high-mobility group (HMG) domains of 11 Sox TFs with Oct4 on...

Full description

Bibliographic Details
Main Authors: Prabhakar, Shyam, Jauch, Ralf, Ng, Calista K. L., Li, Noel X., Chee, Sheena., Kolatkar, Prasanna R.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/101526
http://hdl.handle.net/10220/18725