PPARβ interprets a chromatin signature of pluripotency to promote embryonic differentiation at gastrulation

Epigenetic post-transcriptional modifications of histone tails are thought to help in coordinating gene expression during development. An epigenetic signature is set in pluripotent cells and interpreted later at the onset of differentiation. In pluripotent cells, epigenetic marks normally associated...

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Bibliographic Details
Main Authors: Rotman, Nicolas, Guex, Nicolas, Gouranton, Erwan, Wahli, Walter
Other Authors: Knott, Jason Glenn
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/102143
http://hdl.handle.net/10220/18832