Suprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilization

Suprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilization

Microtubules are a highly validated target in cancer therapy. However, the clinical development of tubulin binding agents (TBA) has been hampered by toxicity and chemoresistance issues and has necessitated the search for new TBAs. Here, we report the identification of a novel cell permeable, tubulin...

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Bibliographic Details
Main Authors: Choi, Bo-Hwa, Chattopadhaya, Souvik, Feng, Lin, Nguyen, Quoc Toan, Lim, Chuan Bian, Harikishore, Amaravadhi, Nanga, Ravi Prakash Reddy, Bharatham, Nagakumar, Zhao, Yan, Yoon, Ho Sup, Thanh, Le Nguyen, Liu, Xuewei
Other Authors: Ko, Ben CB.
Format: Journal Article
Language:English
Published: 2014
Subjects:
DRNTU::Science::Biological sciences::Human anatomy and physiology
Online Access:https://hdl.handle.net/10356/102513
http://hdl.handle.net/10220/24263

Internet

https://hdl.handle.net/10356/102513
http://hdl.handle.net/10220/24263

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