Design of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility

Design of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility

Antimicrobial peptides (AMPs) kill microbes by non-specific membrane permeabilization, making them ideal templates for designing novel peptide-based antibiotics that can combat multi-drug resistant pathogens. For maximum efficacy in vivo and in vitro, AMPs must be biocompatible, salt-tolerant and po...

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Bibliographic Details
Main Authors: Saravanan, Rathi, Li, Xiang, Lim, Kaiyang, Mohanram, Harini, Peng, Li, Mishra, Biswajit, Basu, Anindya, Lee, Jong-Min, Bhattacharjya, Surajit, Leong, Susanna Su Jan
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2014
Subjects:
DRNTU::Engineering::Bioengineering
Online Access:https://hdl.handle.net/10356/102751
http://hdl.handle.net/10220/19188

Internet

https://hdl.handle.net/10356/102751
http://hdl.handle.net/10220/19188

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