Growth inhibition of pathogenic bacteria by sulfonylurea herbicides

Growth inhibition of pathogenic bacteria by sulfonylurea herbicides

Emerging resistance to current antibiotics raises the need for new microbial drug targets. We show that targeting branched-chain amino acid (BCAA) biosynthesis using sulfonylurea herbicides, which inhibit the BCAA biosynthetic enzyme acetohydroxyacid synthase (AHAS), can exert bacteriostatic effects...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Krishna, Aishwarya, Joseph, Thomas L., Wang, Jing, Ong, Catherine, Ooi, Hui Ann, Kreisberg, Jason F., Ong, Nicholas T., Sung, Julie C., Siew, Chern Chiang, Chang, Grace C., Biot, Fabrice, Cuccui, Jon, Wren, Brendan W., Chan, Joey, Sivalingam, Suppiah P., Zhang, Lian-Hui, Verma, Chandra, Tan, Patrick
Muut tekijät: School of Biological Sciences
Aineistotyyppi: Journal Article
Kieli:English
Julkaistu: 2015
Aiheet:
DRNTU::Science::Biological sciences::Microbiology::Bacteria
Linkit:https://hdl.handle.net/10356/102995
http://hdl.handle.net/10220/25811

Internet

https://hdl.handle.net/10356/102995
http://hdl.handle.net/10220/25811

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