Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes

Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes

Insulin resistance and β-cell failure are the major defects in type 2 diabetes mellitus. However, the molecular mechanisms linking these two defects remain unknown. Elevated levels of apolipoprotein CIII (apoCIII) are associated not only with insulin resistance but also with cardiovascular disorders...

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Bibliographic Details
Main Authors: Leibiger, Ingo B., Leibiger, Barbara, Moede, Tilo, Paschen, Meike, Dicker, Andrea, Abdulreda, Midhat H., Åvall, Karin, Ali, Yusuf, Daré, Elisabetta, Köhler, Martin, Ilegems, Erwin, Graham, Mark, Crooke, Rosanne M., Tay, Vanessa Shi Yun, Refai, Essam, Nilsson, Stefan K., Jacob, Stefan, Selander, Lars, Berggren, Per-Olof, Juntti-Berggren, Lisa
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2015
Subjects:
diabetes
apoCIII
insulin resistance
pancreatic islets
Online Access:https://hdl.handle.net/10356/103306
http://hdl.handle.net/10220/25742

Internet

https://hdl.handle.net/10356/103306
http://hdl.handle.net/10220/25742

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