The thrombin-derived host defense peptide GKY25 inhibits endotoxin-induced responses through Interactions with lipopolysaccharide and macrophages/monocytes

The thrombin-derived host defense peptide GKY25 inhibits endotoxin-induced responses through Interactions with lipopolysaccharide and macrophages/monocytes

Host defense peptides have recently gained much interest as novel anti-infectives owing to their ability to kill bacteria and simultaneously modulate host cell responses. The cationic host defense peptide GKY25 (GKYGFYTHVFRLKKWIQKVIDQFGE), derived from the C terminus of human thrombin, inhibits proi...

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Bibliographic Details
Main Authors: Schmidtchen, Artur, Morgelin, Matthias, Hansen, Finja C., Kalle-Brune, Martina, van der Plas, Mariena J. A., Strömdahl, Ann-Charlotte, Malmsten, Martin
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2015
Subjects:
DRNTU::Science::Biological sciences::Microbiology::Immunology
Online Access:https://hdl.handle.net/10356/103339
http://hdl.handle.net/10220/25772

Internet

https://hdl.handle.net/10356/103339
http://hdl.handle.net/10220/25772

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