Incorporating uracil and 5-halouracils into short peptide nucleic acids for enhanced recognition of A–U pairs in dsRNAs

Incorporating uracil and 5-halouracils into short peptide nucleic acids for enhanced recognition of A–U pairs in dsRNAs

Double-stranded RNA (dsRNA) structures form triplexes and RNA-protein complexes through binding to single-stranded RNA (ssRNA) regions and proteins, respectively, for diverse biological functions. Hence, targeting dsRNAs through major-groove triplex formation is a promising strategy for the developm...

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Bibliographic Details
Main Authors: Patil, Kiran M., Ong, Alan Ann Lerk, Krishna, Manchugondanahalli Shivakumar, Toh, Desiree-Faye Kaixin, Yuan, Zhen, Meng, Zhenyu, Shu, Zhiyu, Zhang, Haiping, Lu, Lanyuan, Lu, Yunpeng, Chen, Gang
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2019
Subjects:
DRNTU::Science::Biological sciences
Double-stranded RNA
Enhanced Recognition
Online Access:https://hdl.handle.net/10356/103677
http://hdl.handle.net/10220/47378

Internet

https://hdl.handle.net/10356/103677
http://hdl.handle.net/10220/47378

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