Inhibition of HBV-induced angiogenesis by ibuprofen : role of HBx

Chronic hepatitis B virus (HBV) carriers may develop hepatocellular carcinoma (HCC) by a wide range of mechanisms including angiogenesis. We show that HBV replication induces the expression of angiogenic proteins interleukin 6 (IL6) and cyclooxygenase-2 (Cox2). Interestingly, ibuprofen (a Cox2 inhib...

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Bibliographic Details
Main Authors: Zhang, Jianhua, Chen, William Wei Ning
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/103984
http://hdl.handle.net/10220/17190