Rational engineering of yeast to develop biosensors

The yeast, Saccharomyces cerevisiae, is widely used to produce high value-added chemicals and food ingredients. Typically, genes are either deleted from or added to the yeast to produce a compound-of-interest. However, in doing so, we perturb cellular networks and affect the metabolism of the cell....

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Main Author: Cheng, Penghui
Other Authors: Tan Meng How
Format: Student Research Poster
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/104980
http://hdl.handle.net/10220/25913
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author Cheng, Penghui
author2 Tan Meng How
author_facet Tan Meng How
Cheng, Penghui
author_sort Cheng, Penghui
collection NTU
description The yeast, Saccharomyces cerevisiae, is widely used to produce high value-added chemicals and food ingredients. Typically, genes are either deleted from or added to the yeast to produce a compound-of-interest. However, in doing so, we perturb cellular networks and affect the metabolism of the cell. It will be useful if we can readily determine the concentrations of various chemicals in the cell and dynamically regulate metabolic pathways, so that the cells can cope better. Thus, there is a need to develop biosensors for various chemicals for the yeast cells. [2nd Award]
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spelling ntu-10356/1049802020-09-27T20:29:06Z Rational engineering of yeast to develop biosensors Cheng, Penghui Tan Meng How School of Chemical and Biomedical Engineering Saccharomyces cerevisiae Butanol The yeast, Saccharomyces cerevisiae, is widely used to produce high value-added chemicals and food ingredients. Typically, genes are either deleted from or added to the yeast to produce a compound-of-interest. However, in doing so, we perturb cellular networks and affect the metabolism of the cell. It will be useful if we can readily determine the concentrations of various chemicals in the cell and dynamically regulate metabolic pathways, so that the cells can cope better. Thus, there is a need to develop biosensors for various chemicals for the yeast cells. [2nd Award] 2015-06-16T06:22:37Z 2019-12-06T21:44:00Z 2015-06-16T06:22:37Z 2019-12-06T21:44:00Z 2015 2015 Student Research Poster Cheng, P. (2015, March). Rational engineering of yeast to develop biosensors. Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/104980 http://hdl.handle.net/10220/25913 en © 2015 The Author(s). application/pdf
spellingShingle Saccharomyces cerevisiae
Butanol
Cheng, Penghui
Rational engineering of yeast to develop biosensors
title Rational engineering of yeast to develop biosensors
title_full Rational engineering of yeast to develop biosensors
title_fullStr Rational engineering of yeast to develop biosensors
title_full_unstemmed Rational engineering of yeast to develop biosensors
title_short Rational engineering of yeast to develop biosensors
title_sort rational engineering of yeast to develop biosensors
topic Saccharomyces cerevisiae
Butanol
url https://hdl.handle.net/10356/104980
http://hdl.handle.net/10220/25913
work_keys_str_mv AT chengpenghui rationalengineeringofyeasttodevelopbiosensors