Two combinatorial optimization problems for SNP discovery using base-specific cleavage and mass spectrometry
The discovery of single-nucleotide polymorphisms (SNPs) has important implications in a variety of genetic studies on human diseases and biological functions. One valuable approach proposed for SNP discovery is based on base-specific cleavage and mass spectrometry. However, it is still very challeng...
Main Authors: | , , , |
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Other Authors: | |
Format: | Journal Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/105219 http://hdl.handle.net/10220/16762 |