Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

Our understanding of the conformational and electrostatic determinants that underlie targeting of human leukocyte antigens (HLA) by anti-HLA alloantibodies is principally based upon in silico modelling. Here we provide a biochemical/biophysical and functional characterization of a human monoclonal a...

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Bibliografski detalji
Glavni autori: Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
Daljnji autori: School of Biological Sciences
Format: Journal Article
Jezik:English
Izdano: 2019
Teme:
MHC Class I
Allotransplantation
DRNTU::Science::Biological sciences
Online pristup:https://hdl.handle.net/10356/105503
http://hdl.handle.net/10220/47817

Internet

https://hdl.handle.net/10356/105503
http://hdl.handle.net/10220/47817

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