Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

Our understanding of the conformational and electrostatic determinants that underlie targeting of human leukocyte antigens (HLA) by anti-HLA alloantibodies is principally based upon in silico modelling. Here we provide a biochemical/biophysical and functional characterization of a human monoclonal a...

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Bibliographic Details
Main Authors: Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2019
Subjects:
MHC Class I
Allotransplantation
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/105503
http://hdl.handle.net/10220/47817

Internet

https://hdl.handle.net/10356/105503
http://hdl.handle.net/10220/47817

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