Fabrication of cisplatin-loaded poly(lactide-co-glycolide) composite microspheres for osteosarcoma treatment
Purpose To reduce the toxicity and achieve a sustainable and controllable release of cisplatin (CDDP). Methods CDDP was loaded onto Fe5 (Fe3+ doped hydroxyapatite at atomic ratio of Feadded/Caadded = 5%) nanoparticles through surface adsorption. Subsequently, CDDP-loaded Fe5 nanoparticles (CDDP...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/105525 http://hdl.handle.net/10220/17650 http://dx.doi.org/10.1007/s11095-011-0600-9 |