Effect of A22 on the conformation of bacterial actin MreB

The mechanism of the antibiotic molecule A22 is yet to be clearly understood. In a previous study, we carried out molecular dynamics simulations of a monomer of the bacterial actin-like MreB in complex with different nucleotides and A22, and suggested that A22 impedes the release of Pi from the acti...

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Bibliographic Details
Main Authors: Awuni, Elvis, Mu, Yuguang
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/105780
http://hdl.handle.net/10220/48773