Effect of A22 on the conformation of bacterial actin MreB
The mechanism of the antibiotic molecule A22 is yet to be clearly understood. In a previous study, we carried out molecular dynamics simulations of a monomer of the bacterial actin-like MreB in complex with different nucleotides and A22, and suggested that A22 impedes the release of Pi from the acti...
Main Authors: | , |
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Other Authors: | |
Format: | Journal Article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/105780 http://hdl.handle.net/10220/48773 |