Targeting mechanotransduction mechanisms and tissue weakening signals in the human amniotic membrane

Mechanical and inflammatory signals in the fetal membrane play an important role in extracellular matrix (ECM) remodelling in order to dictate the timing of birth. We developed a mechanical model that mimics repetitive stretching of the amniotic membrane (AM) isolated from regions over the placenta...

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Bibliographic Details
Main Authors: Barrett, David W., John, Rebecca K., Thrasivoulou, Christopher, Mata, Alvaro, Deprest, Jan A., Becker, David Lawrence, David, Anna L., Chowdhury, Tina T.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/106493
http://hdl.handle.net/10220/48950