Cobalt-catalyzed enantioselective directed C-H alkylation of indole with styrenes
A cobalt–chiral phosphoramidite catalyst promotes enantioselective imine-directed C2-alkylation of Boc-protected indoles with styrenes. The reaction affords 1,1-diarylethane products in moderate to good yields with good enantioselectivities under mild conditions. A deuterium-labeling experiment sugg...
| Autores principales: | , |
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| Formato: | Journal Article |
| Lenguaje: | English |
| Publicado: |
2015
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| Acceso en línea: | https://hdl.handle.net/10356/106746 http://hdl.handle.net/10220/25067 |