Carbene-catalyzed asymmetric modification of carboxylic acids and sulfonamides
In this thesis, we demonstrated the new reaction mode enabled by NHC in the enantioselective synthesis of 3-substituted phthalides, which could be used for structural modification on heteroatoms within the medicinally significant molecules. Our method shall expand the synth...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/136869 |