Developing amyloid-β chaperone lipocalin-type prostaglandin D synthase protein as a magnetic resonance active early diagnostic tool
Lipocalin-type prostaglandin D synthase (L-PGDS) is an endogenous brain protein, shown previously as a significant chaperone for amyloid β (Aβ) peptide. It binds to monomeric Aβ as well as mature fibrils and is capable of inhibiting their aggregation. We recently showed that L-PGDS could successfull...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/136881 |