Developing amyloid-β chaperone lipocalin-type prostaglandin D synthase protein as a magnetic resonance active early diagnostic tool

Lipocalin-type prostaglandin D synthase (L-PGDS) is an endogenous brain protein, shown previously as a significant chaperone for amyloid β (Aβ) peptide. It binds to monomeric Aβ as well as mature fibrils and is capable of inhibiting their aggregation. We recently showed that L-PGDS could successfull...

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Bibliografski detalji
Glavni autor: Sharma, Bhargy
Daljnji autori: Konstantin Pervushin
Format: Thesis-Doctor of Philosophy
Jezik:English
Izdano: Nanyang Technological University 2020
Teme:
Online pristup:https://hdl.handle.net/10356/136881