(Guanidine) copper complex-catalyzed enantioselective dynamic kinetic allylic alkynylation under biphasic condition

Highly enantioselective allylic alkynylation of racemic bromides under biphasic condition is furnished in this report. This approach employs functionalized terminal alkynes as pro-nucleophiles and provides 6- and 7-membered cyclic 1,4-enynes with high yields and excellent enantioselectivities (up to...

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Bibliographic Details
Main Authors: Cui, Xi-Yang, Ge, Yicen, Tan, Siu Min, Jiang, Huan, Tan, Davin, Lu, Yunpeng, Lee, Richmond, Tan, Choon-Hong
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/137033