PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy

PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy

Mitophagy is an important type of selective autophagy for specific elimination of damaged mitochondria. PTEN-induced putative kinase protein 1 (PINK1)-catalyzed phosphorylation of ubiquitin (Ub) plays a critical role in the onset of PINK1-Parkin-mediated mitophagy. Phosphatase and tensin homolog (PT...

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Bibliographic Details
Main Authors: Wang, Liming, Cho, Yik-Lam, Tang, Yancheng, Wang, Jigang, Park, Jung-Eun, Wu, Yajun, Wang, Chunxin, Tong, Yan, Chawla, Ritu, Zhang, Jianbin, Shi, Yin, Deng, Shuo, Lu, Guang, Wu, Yihua, Tan, Hayden Weng-Siong, Pawijit, Pornteera, Lim, Grace Gui-Yin, Chan, Hui-Ying, Zhang, Jingzi, Fang, Lei, Yu, Hanry, Liou, Yih-Cherng, Karthik, Mallilankaraman, Bay, Boon-Huat, Lim, Kah-Leong, Sze, Siu-Kwan, Yap, Celestial T., Shen, Han-Ming
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences
PTEN-L
Neurodegenerative Disorders
Online Access:https://hdl.handle.net/10356/137546

Internet

https://hdl.handle.net/10356/137546

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