Carbene-catalyzed indole 3-Methyl C(sp3)-H bond functionalization
The metal-free catalytic functionalization of aromatic sp2-carbons and benzylic sp3-carbons remains challenging. Here we report a carbene-catalyzed functionalization of the 3-methyl sp3-carbon attached to 2-formyl-indoles. The reaction proceeds through an NHC-bound o-quinodimethane as the key interm...
| Үндсэн зохиолчид: | , , , , , , |
|---|---|
| Бусад зохиолчид: | |
| Формат: | Journal Article |
| Хэл сонгох: | English |
| Хэвлэсэн: |
2020
|
| Нөхцлүүд: | |
| Онлайн хандалт: | https://hdl.handle.net/10356/137628 |