Carbene-catalyzed indole 3-Methyl C(sp3)-H bond functionalization
The metal-free catalytic functionalization of aromatic sp2-carbons and benzylic sp3-carbons remains challenging. Here we report a carbene-catalyzed functionalization of the 3-methyl sp3-carbon attached to 2-formyl-indoles. The reaction proceeds through an NHC-bound o-quinodimethane as the key interm...
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Bibliographic Details
| Main Authors: |
Cheng, Jian,
Sun, Jun,
Yan, Jiekuan,
Yang, Song,
Zheng, Pengcheng,
Jin, Zhichao,
Chi, Robin Yonggui |
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| Other Authors: |
School of Physical and Mathematical Sciences |
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| Format: | Journal Article
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| Language: | English |
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| Published: |
2020
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| Subjects: | |
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| Online Access: | https://hdl.handle.net/10356/137628
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